Withington is a suburban area of Manchester, England. It lies 4 miles south of Manchester city centre, and about 0.4 miles south of Fallowfield. Withington was largely rural until the mid-19th century when it experienced rapid socioeconomic development and urbanisation due to the Industrial Revolution, and Manchester's growing level of industrialisation. It officially became part of Manchester in 1904. Due to its close proximity to the University of Manchester and Manchester Metropolitan University it is a very popular area amongst students looking for accommodation. Today, the residents of Withington comprise a mixture of families, university students and affluent "young professionals"—often themselves former students. Due to this diverse range of residents it has become an area of mixed affluence.

Withington has bus links into the Manchester city centre, partly because of its position on the Wilmslow Road bus corridor which is served by very frequent buses and has been said by some analysts to be the busiest in Europe. The majority of services are operated by Stagecoach Manchester. Other bus routes run along Burton Road and Old Moat Lane to the City centre, and there are also bus routes crossing Withington East-West.